Rigid components after removing short-range interactions. (A) Sum of rigid component sizes after removing all interactions below increasing intra-chromosomal distances (98.8% frequency cutoff). (B) Chromosomal locations of rigid components after removing intra-chromsomal interactions that occur within 75kbp for the Duan et al. chromosome conformation graph (98.8% frequency cutoff). Bars indicate centers of the fragments involved in a rigid component, and colors indicate the various components.