From: Regulatory network operations in the Pathway Tools software
E. coli K-12 | B. subtilis | ||||||
---|---|---|---|---|---|---|---|
Gene | Product Role | Score | Direct Targets | Gene | Product Role | Score | Direct Targets |
rpoD | sigma-70 factor | 100 | 2282 | sigA | sigma-43 factor | 100 | 863 |
rpoE | sigma-24 factor | 44 | 550 | sigB | sigma-37 factor | 75 | 101 |
crp | cAMP receptor protein | 36 | 465 | spo0A | response regulator | 55 | 88 |
lexA | SOS response transcriptional repressor | 32 | 56 | sigE | sporulation-specific sigma-29 factor | 51 | 128 |
ihfA | integration host factor, α-subunit | 26 | 225 | spoIVCB | sporulation-specific sigma-K factor precursor (N-terminal half) | 46 | 101 |
ihfB | integration host factor, β-subunit | 26 | 225 | spoIIIC | sporulation-specific sigma-K factor precursor (C-terminal half) | 46 | 101 |
rpoS | sigma-S factor | 26 | 316 | spoIIID | sporulation-specific transcriptional regulator | 46 | 37 |
rpoH | sigma-32 factor | 25 | 450 | gerE | transcriptional regulator | 34 | 104 |
cpxR | stress response regulator | 23 | 58 | abrB | regulator of transition state genes | 25 | 100 |
fis | factor for inversion stimulation | 19 | 223 | sigH | sigma-30 factor | 22 | 21 |
gadX | acid resistance system regulator | 14 | 28 | rok | repressor of comK | 3 | 27 |
fur | ferric uptake regulator | 13 | 131 | comK | competence transcription factor | 3 | 55 |
arcA | anaerobic response regulator | 11 | 160 | degU | two-component response regulator | 1.6 | 19 |
hns | histone-like nucleoid structuring protein | 11 | 174 | codY | GTP and BCAA-dependent transcriptional regulator | 1.6 | 63 |
fnr | aerobic to anaerobic transition regulator | 10 | 294 | sinR | post-exponential phase response regulator | 1.6 | 21 |
dnaA | chromosomal replication initiator protein | 8.2 | 12 | med | positive regulator of comK | 1.6 | 1 |
cytR | cytidine repressor | 8.2 | 12 | scoC | extracellular protease production and sporulation regulator | 0.8 | 16 |
nsrR | nitrite-sensitive repressor | 6.8 | 83 | senS | transcriptional activator | 0.8 | 2 |
rpoN | sigma-54 factor | 6.4 | 179 | salA | Mrp family regulator | 0.4 | 1 |
gadE | acid resistance system regulator | 5.4 | 36 | sigG | sporulation-specific sigma-G factor | 0.4 | 84 |