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Figure 2 | BMC Bioinformatics

Figure 2

From: An algorithm for chemical genomic profiling that minimizes batch effects: bucket evaluations

Figure 2

Shabtai et al. Simplified example of BE implementation. Figure 2| A small-scale example of a basic implementation of BE for scoring experiments: (1) Define bucket sizes and scoring table values. (2) For each experiment, insert the strains in the relevant bucket according to rank. Each strain is mentioned with its bucket definition, while the values in brackets represent the fitness defect score. The fitness defect diagrams represent the buckets according to a coloured rectangle (red for bucket1, green for bucket2, and blue for bucket3). (3) Compare each experiment to the other experiments, and score similarity according to the scoring table. In this example, there is a higher similarity between Exp1-Exp3 rather than Exp2-Exp3. This example demonstrates that the BE algorithm gives greater emphasis to strains with a high fitness defect value rather than strains with a lower value.

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