We calculated the overlaps of the CNEs found in the 154 heart-specific loci and the putative CRMs (PCRMs) with 95 experimentally validated heart enhancers . Columns CNEs and PCRMs display the number of overlaps between the CNEs and heart enhancers, and the PCRMs and heart enhancer, respectively. The expected number is the average overlap between a random CNE set and the heart enhancers. We selected 10000 random sets as before. The P-values were based on the Z-scores calculated from the distribution of the overlaps in the 10000 trials.