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Table 2 The power of epigenetic-effect detection by the epigenetic model and its false positive rates (FPR) under different sample sizes ( n ) and heritabilities ( H 2 )

From: A quantitative genetic and epigenetic model of complex traits

 

n

ae= d1e = d2e

H2 = 0.05

H2 = 0.1

H2 = 0.2

Power

400

0.05

0.055

0.090

0.160

 

1000

0.05

0.090

0.125

0.355

 

2000

0.05

0.115

0.205

0.630

 

5000

0.05

0.215

0.415

0.975

 

1000

0.1

0.085

0.255

0.780

 

2000

0.1

0.265

0.525

0.975

 

5000

0.1

0.495

0.950

1.00

FPR

400

0.05

0.050

0.045

0.065

 

1000

0.05

0.060

0.025

0.045

 

2000

0.05

0.030

0.010

0.045

 

5000

0.05

0.085

0.050

0.070

 

1000

0.1

0.045

0.040

0.040

 

2000

0.1

0.055

0.025

0.030

 

5000

0.1

0.050

0.020

0.045