Table 4 Evaluation of t-test, FEM_minP, FEM_BIC and FEM_ALL methods by simulations
| Type I error (s.e.) | Power (%) (s.e) | Number of DE genes (s.e) | # of variables in Z selected | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Scenario | A | B | C | D | A | B | C | D | A | B | C | D | B | C |
| I |
0.051 (.001) |
0.046 (.001) |
0.049 (.001) |
0.051 (.001) |
67.9 (.006) |
72.9 (.007) |
74.6 (.006) |
69.7 (.006) |
12.5 (1.03) |
20.4 (1.11) |
23.3 (1.04) |
17.6 (1.09) | 0.97/1.97* | 0.78/1.21* |
| II |
0.051 (.001) |
0.052 (.001) |
0.050 (.001) |
0.051 (.001) |
93.8 (.003) |
92.9 (.003) |
92.5 (.003) |
85.0 (.005) |
73.4 (.85) |
73.0 (.92) |
69.8 (.96) |
49.7 (1.37) | 1.7 | 0.59 |
| III |
0.051 (.001) |
0.053 (.001) |
0.051 (.001) |
0.051 (.001) |
93.8 (.003) |
92.5 (.004) |
91.6 (.004) |
85.1 (.005) |
71.8 (.93) |
68.3 (.94) |
66.5 (.88) |
45.8 (1.05) | 1.8 | 0.6 |