The line "2C-SVM" gives MCC-values resulting from a classification of catalytic sites (CAT_sites) with SVMCAT, of ligand-binding sites (LIG_sites) with SVMLIG, and of structurally important sites (STRUC_sites) with SVMSTRUC. The line "CLIPS-1D" shows the performance of the MC-SVM. For FRpred, performance resulting from the analysis of HSSP-MSAs is given. For CAT_sites and LIG_sites, MCC-values are listed resulting from FRcons-cat or FRcons-lig scores of at least 8 or 9, respectively. For STRUC_sites, the same percentage of false positives resulted from FRcons-cat and FRcons-lig predictions.