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Table 4 Performance of CLIPS-1D for different p-values

From: CLIPS-1D: analysis of multiple sequence alignments to deduce for residue-positions a role in catalysis, ligand-binding, or protein structure

Cut-off

Sensitivity

Specificity

Precision

 

CAT

LIG

STRUC

CAT

LIG

STRUC

CAT

LIG

STRUC

0.010

0.170

0.030

0.225

0.996

0.991

0.991

0.316

0.176

0.827

0.025

0.276

0.077

0.445

0.992

0.977

0.977

0.270

0.178

0.789

0.050

0.401

0.137

0.582

0.987

0.954

0.961

0.246

0.165

0.742

  1. The three performance measures were determined (see Methods) by selecting as positive cases all residue-positions with a p-value not greater than the given cut-off. Labels: "CAT" CAT_sites, "LIG" LIG_sites, "STRUC" STRUC_sites.
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BMC Bioinformatics

ISSN: 1471-2105

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