Skip to main content

Table 4 Performance of CLIPS-1D for different p-values

From: CLIPS-1D: analysis of multiple sequence alignments to deduce for residue-positions a role in catalysis, ligand-binding, or protein structure

Cut-off Sensitivity Specificity Precision
  CAT LIG STRUC CAT LIG STRUC CAT LIG STRUC
0.010 0.170 0.030 0.225 0.996 0.991 0.991 0.316 0.176 0.827
0.025 0.276 0.077 0.445 0.992 0.977 0.977 0.270 0.178 0.789
0.050 0.401 0.137 0.582 0.987 0.954 0.961 0.246 0.165 0.742
  1. The three performance measures were determined (see Methods) by selecting as positive cases all residue-positions with a p-value not greater than the given cut-off. Labels: "CAT" CAT_sites, "LIG" LIG_sites, "STRUC" STRUC_sites.