Fitting hidden Markov models of protein domains to a target species: application to Plasmodium falciparum

BMC Bioinformatics

Table 1 New domains in P. falciparum at 10% FDR

	Dom.	Fam.	Abs. P.f.	Abs. Alv.
Pfam	192	132	60	17
Score adjustment	239	159	67	20
Enriched alignment	486	283	101	15
Substitution matrix	228	147	54	18
Match-state clustering	375	243	103	40

Number of new domains (Dom.), domain families of the new domains (Fam.), domain families previously thought to be absent in P. falciparum (Abs. P.f.), and domain families previously thought to be absent in all Alveolata (Abs. Alv.), identified by the correction approaches and the standard Pfam library at 10% FDR.

ISSN: 1471-2105