Figure 1
From: Accuracy of RNA-Seq and its dependence on sequencing depth
Histogram of proportions and peak of histogram of proportion normalization. The peak in the histogram corresponds to the largest density of genes. To determine the peak maximum, the histogram was fitted to a beta function. The blue curve shows the best fit with the maximum at p n = 0.527. This is to be compared to the proportion corresponding to RPKM normalization 0.525.