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Figure 3 | BMC Bioinformatics

Figure 3

From: The human "magnesome": detecting magnesium binding sites on human proteins

Figure 3

The Human Magnesome output. A typical output of the human magnesome site (BAR-hMG). The test sequence inherits, after cluster based HMM alignment to the corresponding templates (listed in the inset), five binding residues (K 21, S 22, T 40, D 63 and T 64). The residues are color coded depending on the BLOSUM 62 alignment scoring matrix. From the result page is also possible to retrieve the matching BAR+ cluster page and the corresponding UniProtKB page of the target entry. The green color in the output indicates residues identical to the original template/s. Similar residues are highlighted in yellow. The yellow star indicates that the protein is located in a cluster where Mg binds to PDB templates (listed) in a documented structural way. Cluster HMM can be downloaded.

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