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Table 1 Human sequences annotated with human structural templates

From: The human "magnesome": detecting magnesium binding sites on human proteins

  Cluster (#) PDB
(#)
Cluster RMSD (Å) Template sequence
(#)
Annotated sequence
(#)
Newly annotated sequence (#) Annotated sequence (ID<30%)*
  $ ^ °       
Mg 8 1 0 9 - 9 55 54 1
Mg and Ions 7 1 0 9 0.30 8 53 52 6
Mg and Ligands 24 4 2 73 0.77 32 159 158 33
Mg , Ions and Ligands 22 5 4 57 0.52 31 1948 1947 19
Mixed 22 6 4 366 0.68 92 473 455 120
Total 83 17 10 514   172 2688 2666 179
  1. Human sequences that inherit annotation from human structural templates are listed as a function of the different typologies of magnesium binding in the PDB files. The table lists the number of clusters, of structural templates, of annotated sequences (sequences that inherit Mg binding positions) according to our procedure, of sequences never annotated before as Mg binding proteins according to UniProtKB and of *sequences annotated when the target/template identity is below the 30%. Three different types of clusters are identified and listed in the first column: $ cluster with structures binding MG with a recognized functional role and whit an EC number, ^ clusters with structures binding MG with a recognized structural role (without an EC number), ° cluster containing structures (119 out of 1,341) binding MG without recognized physiological role.