Figure 3
From: Statistical methods for quantitative mass spectrometry proteomic experiments with labeling
MVA plots. Pre- (panel A) and post-normalization (panel B) within-experiment MVA plots. Pre- (panel C) and post-normalization (panel D) between-experiment MVA plots. The vertical axis is difference between the intensities in two specimens on the log2 scale and the horizontal axis is the average of the two intensities on the log2 scale (note the different in axes labels between the top and bottom plots); there is one point for each peptide observed in both specimens. A locally weighted moving average smoother is indicated to demonstrate the average bias curve as a function of average abundance. A smoothed histogram is included at the bottom of the plots to demonstrate the number of data points represented directly above that area in the plots.