Scalable global alignment for multiple biological networks

BMC Bioinformatics

Table 3 Comparison of quality between our method and IsoRankN

Datasets	DOMAIN		DIP		BioGRID
Algorithms	Ours	IsoRankN	Ours	IsoRankN	Ours	IsoRankN
Coverage	8588	3372	24119	19555	21385	13928
Average similarity score	237.06	174.32	0.00509	0.00426	0.1735	0.0834
Conserved edges rate	.260 (6111 of 23507)	.160 (615 of 3138)	.2209 (17365 of 78611)	.086 (4696 of 54364)	0.1781 (13003 of 72975)	0.0685 (2586 of 37434)
# total enriched GO terms	1026	90	3871	1893	1123	523

The average similarity scores for DOMAIN dataset are computed by equation 2 and the average similarity scores for DIP and BioGRID datasets are normalized BLAST bit scores, computed by equation 1.

ISSN: 1471-2105