Table 1 Benchmarks of BARRIERS, PathwayHunter, Findpath, RNATabuPath, and RNAEAPath for predicting folding pathways between conformational switches on the 18 test cases
From: Predicting folding pathways between RNA conformational structures guided by RNA stacks
Instance | BARRIERS | PathwayHunter | FindPath | RNATabuPath | RNAEAPath | |
|---|---|---|---|---|---|---|
| Â | Â | Â | Â | (n = 1000) | ( n = 1) | ( n = 5) |
rb1 | - | - | 24.04 | 24.04 | 23.2 | 22 |
rb2 | - | 10 | 8.2 | 7.25 | 6.5 | 6.5 |
rb3 | - | - | 22.4 | 17.9 | 17.5 | 16.7 |
rb4 | - | - | 16.9 | 16.9 | 16.9 | 16.9 |
rb5 | - | - | 24.54 | 24.54 | 21.44 | 21.44 |
hok | - | - | 28.5 | 29.66 | 20.7 | 20.1 |
SL | 11.80 | - | 13 | 12.9 | 13.0 | 12.9 |
attenuator | 8.3 | - | 8.7 | 8.6 | 8.7 | 8.5 |
s15 | 6.60 | - | 7.1 | 6.6 | 7.1 | 7.1 |
sbox leader | - | 7.9 | 5.2 | 5.2 | 5.2 | 5.2 |
thiM leader | - | - | 16.13 | 14.84 | 12.3 | 12.3 |
ms2 | - | 11.6 | 6.6 | 6.6 | 6.6 | 6.6 |
HDV | - | 23.53 | 17.4 | 17.0 | 16.8 | 16.8 |
dsrA | 8.0 | - | 8.3 | 8.2 | 8.0 | 8.0 |
ribD leader | - | - | 10.71 | 9.5 | 9.5 | 9.5 |
amv | - | 12.2 | 5.8 | 5.8 | 5.74 | 5.74 |
alpha operon | - | 11.8 | 6.5 | 6.5 | 6.1 | 6.1 |
HIV-1 leader | - | 14.3 | 9.3 | 11.3 | 8.9 | 8.9 |