Modeling a temporal flow cytometric profile. Modeling a temporal flow cytometric profile. (a) Entropy values for a profile combining a given number of components (g) based on the results of the Greedy EM algorithm for Clb5Δ at t = 25 min. (b) Differences between successive entropy values as g increases. (c) DNA distribution for Clb5Δ at t = 25 min, as depicted by a histogram, is modeled with a 2-component skew t-Normal mixture. The orange curve shows the fitted profile while the underlying components are shown in dotted curves.