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Table 5 Cox regression analysis of the five-year breast cancer recurrence of the test samples

From: Gene expression profiling of breast cancer survivability by pooled cDNA microarray analysis using logistic regression, artificial neural networks and decision trees

Item

Univariate

Multivariate

 
 

HR (95% CI)

P

HR (95% CI)

P

NDI

21 Genes Profile

3.53 (2.24-5.58)

<.001

2.60 ( 1.44-4.68)

.001

0.454

Age

0.98 (0.96-1.00)

.115

0.99 (0.977-1.02)

.896

0.012

Tumor Diameter

1.54 (1.21-1.95)

<.001

1.41 (1.07-1.86)

.013

0.121

Histopathologic gradea

4.85 (1.94-12.09)

.001

3.59 (1.41-9.16)

.007

0.182

Estrogen Receptor b

1.50 (1.02-2.20)

.035

1.03 (0.58-1.82)

.902

0.035

  1. Abbreviations: HR, Hazard Ratio. CI, Confidence Interval. P, statistical P value. NDI, Net Reclassification Improvement. a, Histopathologic grade: assessed by the Nottingham grading system. b, Estrogen receptor: negative or positive.