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Table 2 Species-wise and overall comparisons between LASAGNA andClustalW2

From: LASAGNA: A novel algorithm for transcription factor binding site alignment

Species

# better1

# ties2

# TFs3

p-value4

H. sapiens

54 (79.4%)

0

68

4.42×10−7

M. musculus

42 (79.2%)

0

53

1.41×10−5

D. melanogaster

22 (75.9%)

0

29

9.89×10−4

S. cerevisiae

9 (69.2%)

1

13

3.88×10−2

R. norvegicus

20 (76.9%)

1

26

1.54×10−3

Overall

147 (77.8%)

2

189

1.22×10−15

  1. 1. Number of TFs on which LASAGNA performs better thanClustalW2.
  2. 2. Number of TFs on which LASAGNA and ClustalW2 have the sameperformance.
  3. 3. Total number of TFs for a species.
  4. 4. Wilcoxon signed-rank test p-value.
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BMC Bioinformatics

ISSN: 1471-2105

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