Figure 3
From: A flood-based information flow analysis and network minimization method for gene regulatory networks
Pipeline for flooding minimization. (A) Transformation of the regulatory networks for flooding analysis as described in the text. (B) Flooding the network; for a given regulator node u with a positive total incoming fl in the following scenarios are possible for the flood fl(u,v) through the edge (u,v): (i) and (ii) if edge capacity c(u,v) is positive and is greater or smaller than the value of the incoming flood, respectively; (iii) and (iv) if edge capacity c(u,v) is negative and its absolute value is greater or smaller than the value of the incoming flood, respectively; (v) if the total incoming flood flood in is negative, then the node is down-regulated and no flood is propagated regardless of the capacity of the edge. (C) Selection of nodes/links with flood above the threshold and the reverse transformation of the network.