Quality control, analysis and secure sharing of Luminex® immunoassay data using the open source LabKey Server platform

Table 1 Comparison of software tools

	Software
Features	Luminex xPONENT	MiraBio MasterPlex QT	Bio-Plex Manager	GraphPad/Prism	Excel	R	LabKey Server
Graphical user interface	+	+	+	+	+	-	+
Runs a Luminex-type instrument	+	-	+	-	-	-	-
Built-in, automatic quality control flagging of some kind	+	+	+	-	-	-	+
Built-in, automatic curve fits for titrated controls and unknowns, not just standards	+	+	-	-	-	-	+
Built-in mechanism for choosing a standard from a different plate	+	+	+	-	-	-	+
Option of weighting squared errors by to 1/FI²	+	+	+	+	+	+	+
Can subtract blank bead fluorescence	-	-	-	+	+	+	+
Can generate Levey-Jennings plots for cross-run quality control	-	-	-	+	+	+	+
Support for scripting in some language	-	-	-	+	+	+	+
Client APIs for development of custom interfaces	-	-	-	-	+	+	+
Can weight squared errors with custom functions	-	-	-	-	-	+	+
Fully customizable 5pl algorithm	-	-	-	-	-	+	+
Open source	-	-	-	-	-	+	+
Freely available without time restrictions	-	-	-	-	-	+	+
Portal for secure data sharing	-	-	-	-	-	-	+

This table compares LabKey Server with a representative sample of software used for analysis and quality control of research Luminex immunoassays. This list aims to show how LabKey Server provides advantages over other existing software tools, not to compare all capabilities relevant to Luminex analysis. Documentation for many tools was incomplete, so the table provides only a reasonable inference of feature availability.

ISSN: 1471-2105