Figure 3

Overlap between extracted domain-domain interaction sets for different values of parameter α . The graph indicate fractional overlaps between sets of extracted domain-domain interactions (DDIs) for the six different domain annotation schemes defined in Table 2, for different sets of α values. As the underlying set of PPIs, we used a high-confidence yeast PPI data set created by the Interaction Detection Based On Shuffling (IDBOS) procedure at a 5% false discovery rate [8, 41].