Table 2 Enrichment analysis of transcription factor binding sites

Activator protein 1. Signal transduction cascade mediated by glucocorticoids [30]

Activating-protein 2. Regulatory roles in early development, apoptosis and cell-cycle control

Activating transcription factor (class of AP-1 transcription factors dimers).

Transcription factor over-expressed in numerous lung tumor. Known to mediate epithelial-mesenchymal transition and promote invasion.

Cut-like homeodomain protein

Myb proto-oncogene protein. Regulation of cell proliferation/differentiation, regulation of human glucocorticoid receptor [34]

Activating transcription factor 2. <Activation of transcription by interaction with glucocorticoid response elements [33]

cAMP response element-binding protein.

Proto-oncogene c-Rel. Member of the NF- κB family.

Forkhead-related activator. Differential activation of lung specific genes. Involved in cell growth/proliferation mechanisms

GATA-binding protein 1 (globin transcription factor 1). Involved in cell growth, cancer.

Zinc finger protein related factor.

Myeloid zinc finger protein. Control of cell proliferation.

Nuclear factor 1. Chromatin remodeling and transcriptional activation.

Nuclear factor κB. Anti-inflammatory action of steroids [31].

Octamer-binding transcription factor 1.

Olfactory neuron-specific factor.

Stimulating protein 1. Ubiquitous zinc finger transcription factor.

Spermatogenic leucine zipper protein 1.

Signal transducer and activator of transcription. Transcription factors in cytokine-mediated biological responses.

Cellular and viral TATA box elements.

Tax/CREB complex.

Pou domain transcription factor.

Vitellogenin gene-binding protein.