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Table 2 Clinical trials used to calibrate virtual populations with MAPEL

From: Alternate virtual populations elucidate the type I interferon signature predictive of the response to rituximab in rheumatoid arthritis

Therapy Trial in MTX-IR patients
Rituximab, 1000 mg/kg, background MTX [22]
Tocilizumab, 4 & 8 mg/kg, background MTX LITHE [23], OPTION [24]
Anti-TNF (infliximab 3 & 10 mg/kg, adalimumab 40 mg/kg), background MTX ATTRACT [6, 25], ATTEST [26]