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Table 12 Comparing four algorithms using different coverage cutoffs for dbSNPs and non-dbSNPs

From: Comparing a few SNP calling algorithms using low-coverage sequencing data

A. dbSNPs

Coverage cutoffs

Total

By 1

By 2

By 3

By 4

≥ 3X

592

108 (18.24%)

82 (13.85%)

125 (21.11%)

277 (46.79%)

≥ 4X

276

68 (24.64%)

32 (11.59%)

50 (18.12%)

126 (45.65%)

≥ 5X

201

61 (30.35%)

20 (9.95%)

33 (16.42%)

87 (43.28%)

≥ 6X

169

54 (31.95%)

15 (8.88%)

33 (19.53%)

67 (39.64%)

≥ 7X

153

53 (34.64%)

15 (9.80%)

29 (18.95%)

56 (36.60%)

≥ 8X

134

43 (32.09%)

12 (8.96%)

29 (21.64%)

50 (37.31%)

≥ 9X

123

38 (30.89%)

15 (12.20%)

25 (20.33%)

45 (36.59%)

≥ 10X

110

34 (30.91%)

11 (10.00%)

27 (24.55%)

38 (34.55%)

B. non-dbSNPs

Coverage cutoffs

Total

By 1

By 2

By 3

By 4

≥ 3X

402

151 (37.56%)

99 (24.63%)

76 (18.91%)

76 (18.91%)

≥ 4X

211

76 (36.02%)

41 (19.43%)

53 (25.12%)

41 (19.43%)

≥ 5X

161

57 (35.04%)

30 (18.63%)

37 (22.98%)

37 (22.98%)

≥ 6X

127

38 (29.92%)

27 (21.26%)

29 (22.83%)

33 (25.98%)

≥ 7X

106

33 (31.13%)

21 (19.81%)

22 (20.75%)

30 (28.30%)

≥ 8X

93

32 (34.41%)

17 (18.28%)

22 (23.66%)

22 (23.66%)

≥ 9X

87

28 (32.18%)

16 (18.39%)

23 (26.44%)

20 (22.99%)

≥ 10X

79

25 (31.65%)

18 (22.78%)

20 (25.32%)

16 (20.25%)

  1. “Total” means the total number of SNVs called by four algorithms. “By 1” means the number (percentage) of SNVs called by only one of the four algorithms. “By 2” means the number (percentage) of SNVs called by any two algorithms. “By 3” means the number (percentage) of SNVs called by any three algorithms. “By 4” means the number (percentage) of SNVs called by four algorithms.