Figure 5
From: ScreenSifter: analysis and visualization of RNAi screening data
Screen comparison. (A) Scatter plot of average control-normalized luciferase signals of PE vs Ricin, with controls highlighted. (B) Scatter plot of average control-normalized luciferase signals of PE vs Ricin, color-coded according to toxin-specificity. (C) ERAD protein-protein interaction network displaying Ricin specificity, demonstrating the identification of a gene below but close to the chosen threshold (ERLIN2), and a potential false negative gene (VCP). (D) Cullin-Ring Ligase complex protein-protein interaction network displaying PE specificity.