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Figure 2 | BMC Bioinformatics

Figure 2

From: Parametric sensitivity analysis for biochemical reaction networks based on pathwise information theory

Figure 2

Molecule concentration of p53, Mdm2-precursor and Mdm2. Concentration oscillations as well as time delays (phase shifts) between the species are present due to the negative feedback loop. Furthermore, the concentration of p53 periodically approaches zero and since negative concentrations are not allowed, the stochastic characteristics of p53 are far from Gaussian.

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BMC Bioinformatics

ISSN: 1471-2105

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