Figure 2

Phenotype identification with PhenoDissim. A) Distributions of phenotypic dissimilarity of the controls, with siUBC (red), siCLSPN (purple) and siRLUC (blue). B) The correlation between two replicates. Replicate 1 of all treatments including samples and controls is plotted on the X axis and replicate 2 on the Y axis. siUBC treatments are in red, siCLSPN in purple and siRLUC in blue. All samples are in gray, with the strongest phenotypes in black and labeled with gene names. C) Cell images of the controls (siUBC, siCLSPN, siUBC) and three phenotype hits (siPLK1, siCOPB2, siAKAP7).