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Table 2 Main properties of the metabolic networks used in this paper (from BIGG http://bigg.ucsd.edu/ )

From: Partial inhibition and bilevel optimization in flux balance analysis

 

E.coli core

S.aureus

H.pylori

S.oneidensis

E.coli

S.typhimurium

Number of reactions

95

575

513

696

1911

2224

Number of metabolites

72

455

436

528

1337

1497

Number of genes

137

619

339

783

1261

1271

Number of drugs

8

-

-

-

-

-

Reference

[35]

[36]

[37]

[38]

[39]

[40]

  1. For the E.coli core network, drugs and respective targets have been selected from DrugBank database [41]: drugs which are common metabolites (for example Adenosine) have been discarded and drugs with the same targets have been grouped.