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Table 2 Estimates of the mean time of alteration in cell divisions with its 90% CI for the driver genes from lung data

From: Using passenger mutations to estimate the timing of driver mutations and identify mutator alterations

Gene

Mean time of alteration in cell divisions

90% CI

APC

379

(44,801)

ATM

594

(93,805)

EGFR

23

(18,93)

KRAS

280

(158,392)

LRP1B

549

(443,917)

NF1

505

(60,744)

PRKDC

466

(324,1637)

PTPRD

801

(394,1228)

STK11

259

(108,455)

TP53

323

(208,456)

  1. The mean time of alteration for each gene is calculated by averaging the posterior mean of the alteration time of the gene among samples in which it is altered.
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BMC Bioinformatics

ISSN: 1471-2105

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