Table 2 Estimated powers of the four methods at significant level 0.05 under different parameter settings for the three-component mixture distributions with τ 1  = 0.1, τ 2  = 0.9
From: Age-adjusted nonparametric detection of differential DNA methylation with case-control designs
Parameter Setting | π 1 | π 2 | π 3 | μ | σ | t-test | Linear regression | Wilcox | BWS |
|---|---|---|---|---|---|---|---|---|---|
δ μ  = 0.03 | 0.3 | 0.5 | 0.2 | 0.3 | 0.1 | 0.475 | 0.479 | 0.749 | 0.836 |
δ μ  = 0.05 | 0.3 | 0.5 | 0.2 | 0.3 | 0.1 | 0.889 | 0.892 | 0.951 | 0.988 |
δ τ  = 0.03 | 0.45 | 0.1 | 0.45 | 0.5 | 0.05 | 0.048 | 0.047 | 0.078 | 0.727 |
δ τ  = 0.06 | 0.45 | 0.1 | 0.45 | 0.5 | 0.05 | 0.048 | 0.047 | 0.092 | 0.877 |