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Table 2 Estimated powers of the four methods at significant level 0.05 under different parameter settings for the three-component mixture distributions with τ 1 = 0.1, τ 2 = 0.9

From: Age-adjusted nonparametric detection of differential DNA methylation with case-control designs

Parameter Setting π 1 π 2 π 3 μ σ t-test Linear regression Wilcox BWS
δ μ  = 0.03 0.3 0.5 0.2 0.3 0.1 0.475 0.479 0.749 0.836
δ μ  = 0.05 0.3 0.5 0.2 0.3 0.1 0.889 0.892 0.951 0.988
δ τ  = 0.03 0.45 0.1 0.45 0.5 0.05 0.048 0.047 0.078 0.727
δ τ  = 0.06 0.45 0.1 0.45 0.5 0.05 0.048 0.047 0.092 0.877