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Table 2 The proportion of non-enriched GO terms and the log2 odds ratios of GO terms used in the simulation studies

From: Empirical Bayes estimation of posterior probabilities of enrichment: A comparative study of five estimators of the local false discovery rate

Number of GO terms Π 0 log2 odds ratio (ϕ i )  
   0.5, i = 1
2 50.0% 0, i = 2
  100.0% 0, i = 1,2
   3, i = 1
  50.0% −3, i = 2
   0, i = 3,4
   0.5, i = 1
4 75.0% 0, i = 2,…,4
  100.0% 0, i = 1,…,4
   (0.5 +1.5×(i − 1)), i=1,2
  50.0% −(0.5 +1.5×(i − 3)), i = 3,4
   0, i = 5,…,8
   (0.5 +1.5×(i − 1)), i = 1,2
  62.5% −(0.5 +1.5×(i − 2)), i = 3
   0, i = 4,…,8
   2, i = 1
8 75.0% −2, i = 2
   0, i=3,…,8
   2, i = 1
  87.5% 0, i = 2,…,8
  100.0% 0, i = 1,…,8
   (0.32 +0.64×(i − 1)), i = 1,…,8
  50.0% −(0.32 +0.64×(i − 9)), i = 9,…,16
   0, i = 17,…,32
   (0.8 +0.8×(i − 1)), i = 1,…,3
  62.5% −(0.8 +0.8×(i − 4)), i = 4,…,6
   0, i = 7,…,32
   (0.2 +1.6×(i − 1)), i = 1,2
32 75.0% −(0.2 +1.6×(i − 1)), i = 3,4
   0, i = 5,…,32
   1.8, i = 1
  87.5% −1.8, i = 2
   0, i = 3,…,32
  100.0% 0, i = 1,…,32
  1. Here, index i labels the GO term.
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BMC Bioinformatics

ISSN: 1471-2105

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