Estimate hidden dynamic profiles of siRNA effect on apoptosis

BMC Bioinformatics

Table 4 Correlation between measurements calculated from the estimated dynamics of siRNA strength

	Diff.	siRNA	Height	c	d	PC1
Diff.	1.0	0.99922	0.97268	0.97605	0.68269	0.69267
siRNA		1.0	0.97307	0.96764	0.66965	0.67984
height			1.0	0.92129	0.50365	0.51537
c				1.0	0.79264	0.80059
d					1.0	0.99989
PC1						1.0

Peason’s correlation coefficients between the area under the curve (AUC) for differences in the cell population between siRNA treatments and the negative control (Diff.), AUC of siRNA strength (siRNA), the highest points of siRNA strength curves (height), model parameters c and d, and the loading values of siRNAs on the first principal component (PC1), as derived from six values of each c and d by PCA.

ISSN: 1471-2105