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Table 2 Semantic similarity analysis of tested genes.

From: SNPranker 2.0: a gene-centric data mining tool for diseases associated SNP prioritization in GWAS

OMIM Disorder

Gene Symbol

Similarity score

 

Input Gene

Known Associated

 

B-Cell Cll/Lymphoma 2

BCL2

CDKN2A

0.389

  

MYC

0.305

  

TP53

0.434

  

BRCA1

0.382

  

BRCA2

0.329

  

CCND1

0.247

  

ATM

0.370

Bipolar disorder

KLF12

RORA

0.636

  

RORB

0.759

  

ARNTL

0.636

  

HTR2A

0.301

  1. Given two scenarios of different disorders, the table shows the similarities, computed using the Wang metrics score, among genes that are known to be associated with the pathologies and the ontologically enriched output gene lists.
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BMC Bioinformatics

ISSN: 1471-2105

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