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Table 4 Comparison of four methods on aligning the PPI networks of KSHV and VZV

From: BinAligner: a heuristic method to align biological networks

Method

nEdge

nOrth

EC

OP

P-value

GRAAL

45

2

39.1%

12.5%

2.6 × 10−19

GraphAlignment

51

9

44.3 %

56.3%

4.3 × 10−25

IsoRank

48

15

41.8%

93.8%

4.1 × 10−22

BinAligner(S)

68

0

59.1%

0

6.2× 10−44

BinAligner

58

16

50.4%

100%

1.0 × 10−32

  1. BinAligner(S) means pure graph structure alignment using BinAligner; nEdge denotes the number of aligned matched edges; nOrth denotes the number of aligned orthologous pairs; EC denotes edge correctness and OP denotes orthologous percentage.
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BMC Bioinformatics

ISSN: 1471-2105

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