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Table 4 Comparison of four methods on aligning the PPI networks of KSHV and VZV

From: BinAligner: a heuristic method to align biological networks

Method nEdge nOrth EC OP P-value
GRAAL 45 2 39.1% 12.5% 2.6 × 10−19
GraphAlignment 51 9 44.3 % 56.3% 4.3 × 10−25
IsoRank 48 15 41.8% 93.8% 4.1 × 10−22
BinAligner(S) 68 0 59.1% 0 6.2× 10−44
BinAligner 58 16 50.4% 100% 1.0 × 10−32
  1. BinAligner(S) means pure graph structure alignment using BinAligner; nEdge denotes the number of aligned matched edges; nOrth denotes the number of aligned orthologous pairs; EC denotes edge correctness and OP denotes orthologous percentage.