Figure 5

Proportion of Type 2 compensatory substitutions. The analytical prediction of the probability of Type 2 events from Equation 11 (black lines) compares favorably to simulations without recombination (blue circles). Simulations with recombination are depicted as well (red triangles). (A) θ = 1 (B) θ = 0.1 (C) θ = 0.01 (D) θ = 0.001