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Figure 11 | BMC Bioinformatics

Figure 11

From: Identifying conserved protein complexes between species by constructing interolog networks

Figure 11

Comparison between using Ensembl and OrthoMCL in constructing the interolog network. Ensembl [17] contains protein orthologs based on sequence similarity as well as domain information, while OrthoMCL [18] is predominantly based on sequence similarity. As we can see from the table, using domain information (through Ensembl) generates significantly more many-to-many ortholog mappings thereby enhancing our interolog construction.

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