Table 2 Top biofunctions calculated (Ingenuity Pathways Analysis) from gene list generated by comparison of SQ20B-AH20 and SQ20B-WT for genes differentially expressed at p< 0.05 (Benjamini and Hochberg multiple testing correction) and fold difference ≥1.5
Diseases and Disorders | p-value | # Molecules |
|---|---|---|
Dermatological Diseases and Conditions | 2.00E-08 – 1.47E-02 | 59 |
Cancer | 1.90E -07 – 1.55E-02 | 103 |
Reproductive System Disease | 2.31E -07 – 1.48E-02 | 54 |
Endocrine System Disorders | 3.17E-07 – 2.29E-03 | 28 |
Inflammatory Responses | 7.32E-06 – 1.62E-02 | 48 |
Molecular and Cellular Functions | ||
Cellular Movement | 5.75E-06 – 1.62E-02 | 61 |
Lipid Metabolism | 6.04E-05 – 1.47E-02 | 24 |
Molecular Transport | 6.04E-05 – 1.59E-02 | 41 |
Small Molecule Biochemistry | 6.04E-05 – 1.51E-02 | 36 |
Cell-To-Cell Signaling and Interaction | 8.26E-05 – 1.59E-02 | 46 |