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Table 9 Comparison with other methods

From: Sequence-only evolutionary and predicted structural features for the prediction of stability changes in protein mutants

Method

Data set

Q (%)

MCC

P (%)

R (%)

FPR (%)

r

RMSE

Cheng et al. [3]

1,496 (1,539)

84.1

0.59

69.3

71.1

10.3

(0.75)

(1.10)

Our method

 

86.0

0.65

77.0

72.3

8.6

(0.83)

(0.93)

Huang et al. [4]

1,859

82.1

-

-

75.3

15.5

0.70

-

Our method

 

83.4

0.61

75.2

70.3

10.6

0.80

1.08

Ozen et al. [5]

1,122

83.9

-

-

-

-

-

-

Our method

 

84.6

0.65

77.6

75.1

10.7

0.82

0.97