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Table 14 Summary of findings

From: Investigating mathematical models of immuno-interactions with early-stage cancer under an agent-based modelling perspective

Case Study

Outcome of the comparison

Explanation

Population size

1) Tumour/Effector

• Most results were different

• It appears that variabilities in small populations have major impacts in the outcomes

Varied from 5 to 600

2) Tumour/Efector

• Results were statistically/IL-2 the same

• Large populations

• Less variability in the agents' populations

104

3) Tumour/Effector/ IL-2/ TGF-β

• Different runs with outcome variations

• Simulations produced alternative scenarios

• The behaviour of the curves is less erratic for agents

• Agent-based stochasticity

• New scenarios need further investigations to assess their feasibility

• Large numbers of agents

104