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Table 8 Transition rates calculations from the mathematical equations for case 2

From: Investigating mathematical models of immuno-interactions with early-stage cancer under an agent-based modelling perspective

Agent

Transition

Mathematical equation

Transition rate

Effector Cell

Reproduce

p 1 . I L E g 1 + I L _ 2

p 1 . T o t a l I L _ 2 . T o t a l E f f e c t o r g 1 + T o t a l I L _ 2

 

Die

μ 2 E

mu 2

 

killTumour

a a E T g 2 + T

a a T o t a l T u m o u r g 2 + T o t a l T u m o u r

 

ProduceIL2

p 2 E T g 3 + T

p 2 . T o t a l T u m o u r g 3 + T o t a l T u m o u r

Tumour Cell

Reproduce

aT(1 - bT )

a - (TotalTumour.b)

 

Die

aT(1 - bT )

a - (TotalTumour.b)

 

DieKilledByEffector

a a T E g 2 + T

message from effector

IL-2

Loss

μ 3 I L

mu 3