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Table 3 Performance of Oli , OliMo , OliMoSS , RNAcontext and both RPISeq methods on PUM2+ in combination with two different negative datasets

From: Protein-specific prediction of mRNA binding using RNA sequences, binding motifs and predicted secondary structures

Pos. data

Neg.data

Value

Oli

OliMo

OliMoSS

RNAcontext

RPISeq-SVM

RPISeq-RF

PUM2+

PUM2-

AUC

0.77

0.77

0.74

0.75

0.73

0.52

  

Prec

0.73

0.73

0.69

0.59

0.48

0.42

PUM2+

3K-

AUC

0.84

0.84

0.82

0.83

0.77

0.56

  

Prec

0.80

0.80

0.74

0.68

0.47

0.40

  1. The table shows the performance for each method on two different datasets: one with PUM2+ and experimental negatives PUM2- and one with PUM2+ and randomly selected 3’-UTRs 3K-. AUC and precision (Prec) values were calculated for a 10-fold cross validation.
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BMC Bioinformatics

ISSN: 1471-2105

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