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Table 3 The GSA result by a simple cross-species GSA (case example 1)

From: gsGator: an integrated web platform for cross-species gene set analysis

Rank

Set size

Overlap

P-value

Q-value

Mouse phenotype

1

22

3

3.3E-10

2.5.E-06

Decreased eye pigmentation

2

30

3

8.7E-10

3.3.E-06

Abnormal eye pigmentation

3

51

3

4.5E-09

1.1.E-05

Abnormal skin pigmentation

4

76

3

1.5E-08

2.8.E-05

Diluted coat color

5

87

3

2.3E-08

3.4.E-05

Abnormal coat/hair pigmentation

6

5

2

5.2E-08

5.6.E-05

Absent eye pigmentation

7

5

2

5.2E-08

5.6.E-05

Ocular albinism

8

7

2

1.1E-07

1.0.E-04

Variegated coat color

9

8

2

1.5E-07

1.1.E-04

Abnormal choroid melaningranule morphology

10

8

2

1.5E-07

1.1.E-04

Mottled coat

11

9

2

1.9E-07

1.3.E-04

Abnormal melanogenesis

12

18

2

7.9E-07

5.0.E-04

Yellow coat color

13

24

2

1.4E-06

8.3.E-04

Abnormal melanosome morphology

14

27

2

1.8E-06

9.8.E-04

Irregular coat pigmentation

15

31

2

2.4E-06

1.2.E-03

Hypopigmentation

16

87

2

1.9E-05

9.1.E-03

Prenatal lethality

17

975

3

3.2E-05

1.4.E-02

Decreased body size

18

125

2

4.0E-05

1.7.E-02

Infertility

19

237

2

1.4E-04

5.4.E-02

Increased susceptibility to bacterial infection

20

365

2

3.4E-04

9.1.E-02

Complete prenatal lethality

21

519

2

6.8E-04

1.1.E-01

Male infertility

22

574

2

8.3E-04

1.3.E-01

Complete postnatal lethality

23

1258

2

3.9E-03

2.9.E-01

Premature death

24

1642

2

6.5E-03

3.9.E-01

No abnormal phenotype detected

  1. The related annotations to eye color is indicated in bold type.