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Figure 1 | BMC Bioinformatics

Figure 1

From: A highly conserved WDYPKCDRA epitope in the RNA directed RNA polymerase of human coronaviruses can be used as epitope-based universal vaccine design

Figure 1

Conserved peptide in RNA directed RNA polymerase. Multiple sequence alignment of the 46 replicase polyprotein 1ab of all coronaviruses revealed that human coronaviruses are conserved in RNA directed RNA polymerase. This alignment was visualized by Jalview 2.8 [25]. Along the alignment this tool provides a graphical (bar chart) conservation summery using 11-base scale for conservancy and BLOSUM 62 for quality. For Conservation yellow color bar and star sign indicates the full conservation. Black bars showed the consensus sequence and yellow color indicates good quality. All the colors changes according to the conservation and alignment quality.

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BMC Bioinformatics

ISSN: 1471-2105

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