Figure 2

Secretion systems search results. (A) A search for B. mallei (strain ATCC 23344) type 3 secretion system proteins yields a list of pathogen proteins associated with that secretion system. The content of the list can be filtered by cluster type and mechanisms of action, e.g., by the animal-associated T3SS cluster and the actin cytoskeleton rearrangement mechanism. (B) The genome browser shows the location of the bacterial proteins associated with the secretion system on the bacterial reference sequence. (C) Users can visualize host-pathogen protein-protein interactions (PPIs) with the help of the PPI browser. Interactions are represented in the form of networks, where proteins correspond to network nodes (blue circles and red squares), and interactions between those proteins correspond to network edges (gray and green lines).