Figure 5
![Figure 5](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2F1471-2105-15-248/MediaObjects/12859_2014_Article_6518_Fig5_HTML.jpg)
Patient HPO annotation information content impact. The causative gene mean rank when ranked by similarity score as a function of the maximum information content, IC, of all HPO terms used to describe the patient. Higher information content indicates higher term specificity.