A continuous optimization approach for inferring parameters in mathematical models of regulatory networks

BMC Bioinformatics

Table 3 Summary of the robustness property of the three models with estimated model parameters

	ERK kinase module	G1/S transition module	MAP kinase pathway
The number of the absolute criteria	4	4	0
The number of the relative criteria	4	4	4
Better continuous absolute criteria	CAE1, CAE3, CAE4	CAE1, CAE3	N/A
Better discrete absolute criteria	0	DAE2, DAE4	N/A
Better continuous relative criteria	CRE2, CRE3, CRE4	CRE4	CRE1, CRE2, CRE3
Better discrete relative criteria	DRE1	DRE1, DRE2, DRE3	DER4

The comparison of discrete and continuous approaches is mainly based on the magnitude of the mean errors of these approaches which are given in Additional file 1: Tables S6, S7 and S8.

ISSN: 1471-2105