Table 2 The inhibitory activity profiles of curcumin analogs on MCF7 and SKBR3 cells
From: Computational analyses of curcuminoid analogs against kinase domain of HER2
| Â | SKBR3 | MCF7 | Â | SKBR3 | MCF7 |
|---|---|---|---|---|---|
AS-KTC | IC50 | IC50 | AS-KTC | IC50 | IC50 |
|  | (μM) | (μM) |  | (μM) | (μM) |
001 | 8.3 ± 0.6 | 41.9 ± 12.3 | 013 | > 100 | > 100 |
002 | 13.0 ± 1.8 | 44.4 ± 10.8 | 014 | 10.8 ± 5.5 | 9.9 ± 3.5 |
003 | 24.9 ± 2.3 | 81.6 ± 26.0 | 015 | 30.9 ± 4.5 | 15.4 ± 3.8 |
004 | > 100 | 79.4 ± 9.8 | 016 | 42.6 ± 5.5 | 33.8 ± 5.8 |
005 | > 100 | > 100 | 017 | 21.3 ± 3.8 | 14.3 ± 1.9 |
006 | 15.4 ± 3.9 | > 100 | 018 | 33.8 ± 7.2 | 22.4 ± 7.7 |
007 | 7.9 ± 2.5 | 17.5 ± 4.5 | 019 | > 100 | 38.9 ± 9.1 |
008 | 7.9 ± 2.5 | 36.7 ± 5.8 | 020 | 25 ± 5.5 | 44.1 ± 9.0 |
009 | 8.2 ± 0.4 | 22.1 ± 0.1 | 021 | 16.9 ± 3.4 | > 100 |
010 | > 100 | > 100 | 022 | > 100 | > 100 |
011 | > 100 | > 100 | 023 | > 100 | 24.3 ± 8.7 |
012 | 9.9 ± 1.0 | 14.3 ± 1.6 | 024 | > 100 | > 100 |