Table 2 A feature summary of Mercury in DNAnexus and similar tools and services
| Â | Mercury in DNAnexus | Galaxy | Seven bridges | Chipster | Anduril |
|---|---|---|---|---|---|
Mapper | BWA | No canonical (many) | BWA | BWA | BWA/Bowtie |
Variant caller | Atlas2 | No canonical (many) | GATK | Samtools mpileup | Samtools/GATK, Varscan |
Annotation | Cassandra | snpEff, AlleleFrequency | snpEff, ANNOVAR | Bioconductor | ANNOVAR |
Visualization | Built-in browser | Built-in browser | Links to IGV | Built-in browser | No |
Runs on local hardware | No* | Yes | No | Yes | Yes |
Runs on cloud infrastructure | Yes | Yes | Yes | Jobs queued to public server | No |
HIPAA compliant | Yes | No | No | No | Not Applicable (local only) |
Requires setup configuration | No | Yes | No | Yes | Yes |
Can add tools independently | Yes | Yes | By request | No | No |
Data sharing & collaboration | Yes | Yes | No | No | No |