Figure 3
From: Polyphony: superposition independent methods for ensemble-based drug discovery
Cα-trace κ/τ variation compared to two other metrics of backbone variation (a) Root mean squared fluctuation (RMSF) in Cα position after least squares fitting a sliding window of 5 residues to a reference structure and (b) variation in φ/ψ torsion angle (see equation 1). Labels show alignment position numbers indicating that the largest differences lie largely in the T-loop (145–164).