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Table 4 Distribution comparisons of the p-values of protein modules obtained from different algorithms on DIP

From: MAE-FMD: Multi-agent evolutionary method for functional module detection in protein-protein interaction networks

p-values

Algorithms

Distribution ranges

Ratio

  

(0,1 .0 e−30]

(1 .0 e−30,1 .0 e−20]

(1 .0 e−20,1 .0 e−10]

(1 .0 e−10,1 .0 e−3]

(1 .0 e−3,0 .05]

(0 .05,1]

 
 

MAE-FMD

4

12

33

100

35

17

0.859

 

CFinder

3

4

26

80

32

15

0.925

Biological

Coach

1

2

57

213

74

24

0.966

Process

NACO-FMD

2

5

28

158

96

40

0.810

 

MCL

1

5

35

180

110

57

0.733

 

HAM-FMD

2

3

27

139

64

25

0.878

 

MCODE

0

1

15

55

11

3

0.966

 

MAE-FMD

7

14

30

76

28

22

0.756

 

CFinder

5

6

18

76

18

10

0.769

Cellular

Coach

2

9

54

187

60

26

0.880

Component

NACO-FMD

2

9

34

137

61

38

0.692

 

MCL

3

11

38

144

67

55

0.601

 

HAM-FMD

1

6

35

109

51

23

0.760

 

MCODE

0

1

21

42

8

7

0.898

 

MAE-FMD

4

6

22

72

38

20

0.692

 

CFinder

1

3

13

63

36

15

0.757

Molecular

Coach

1

1

20

128

108

45

0.789

Function

NACO-FMD

1

2

19

108

69

47

0.606

 

MCL

1

3

22

102

84

50

0.495

 

HAM-FMD

0

1

15

94

59

32

0.679

 

MCODE

0

0

8

39

13

12

0.818